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Increased core body temperature in astronauts during long-duration space missions
Alexander C Stahn1,2, Andreas Werner3, Oliver Opatz1
1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Physiology, Center for Space Medicine and Extreme Environments, CharitéCrossOver (CCO), Charitéplatz 1, Berlin, 10117, Germany.
Astronauts experience higher core body temperature (CBT) during exercise in space. Long-duration spaceflight also leads to a sustained increase in resting CBT, impacting health and performance.
Area of Science:
- Human physiology
- Space medicine
- Thermoregulation
Background:
- Human core body temperature (CBT) is tightly regulated.
- Terrestrial factors affecting CBT are well-studied.
- Effects of weightlessness on human thermoregulation remain unclear, especially during long-duration spaceflight.
Purpose of the Study:
- Investigate the impact of long-duration spaceflight on human thermoregulation.
- Assess changes in CBT at rest and during exercise in astronauts.
Main Methods:
- Monitoring astronaut core body temperature (CBT) during rest and exercise.
- Analyzing physiological markers, including anti-inflammatory proteins.
Main Results:
- Core body temperature (CBT) rises higher and faster during exercise in space compared to Earth.
- A sustained increase in resting CBT (approx. 1°C) was observed over 2.5 months.
- This increase was linked to elevated levels of interleukin-1 receptor antagonist.
Conclusions:
- Long-duration spaceflight alters human thermoregulation, affecting both resting and exercise states.
- Elevated CBT poses risks to astronaut health, cognitive function, and performance.
- Findings challenge assumptions about the human thermoregulatory set point and adaptability to environmental changes.
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