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Fatal haemopathological consequences of general anaesthesia
P J Wright1, J R Shortland, J D Stevens
1Department of Anaesthetics, Royal Hallamshire Hospital, Sheffield.
British Journal of Anaesthesia
|January 1, 1989
Abstract:
A previously healthy 63-yr-old female died following an anaphylactoid response to anaesthesia with thiopentone and suxamethonium. Postmortem findings strongly suggested that disseminated intravascular coagulation played a significant role in her death. The local mechanism behind the reaction is unknown, but the formation of thiopentone-suxamethonium colloid aggregates during induction, may have led to "aggregate anaphylaxis".