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[Medication rules for prescriptions containing Pterocephali Herba based on data mining].

Fang Zuo1, Zhi-Cheng Wei1, Ce Tang1

  • 1Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|November 25, 2017
PubMed
Summary
This summary is machine-generated.

This study analyzed Tibetan medicine prescriptions containing Pterocephali Herba, revealing its common use for fever, viral infections, and arthritis. Key combinations include Corydalis Herba, Lagotidis Herba, and Gentianae Macrophyllae Radix for treating damp-heat toxin conditions.

Keywords:
Pterocephali Herbaassociation rulesdata miningmedication rulestraditional Chinese medicine inheritance support system

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Area of Science:

  • Tibetan Medicine
  • Pharmacology
  • Data Mining in Traditional Medicine

Background:

  • Pterocephali Herba is a component in traditional Tibetan medicine.
  • Understanding its prescription patterns is crucial for clinical application and research.

Purpose of the Study:

  • To analyze medication rules and identify core drug combinations for prescriptions containing Pterocephali Herba.
  • To investigate the therapeutic applications and pharmacological actions of Pterocephali Herba in Tibetan medicine.

Main Methods:

  • Utilized the Traditional Chinese Medicine Inheritance Support system (V2.0.1) for data mining.
  • Applied association rules and the Apriori algorithm to analyze 215 prescriptions involving 376 herbs.
  • Conducted frequency statistics on single drugs and drug combinations.

Main Results:

  • Pterocephali Herba prescriptions commonly treat cold fever, distemper virus, and arthritis.
  • Frequently used accompanying herbs include Corydalis Herba, Lagotidis Herba, and Gentianae Macrophyllae Radix.
  • Common drug combinations are Pterocephali Herba with Corydalis Herba, Lagotidis Herba, or Gentianae Macrophyllae Radix, primarily targeting damp-heat toxin conditions.

Conclusions:

  • Prescriptions containing Pterocephali Herba are predominantly used for conditions like Tourette syndrome, fever, and arthritis, often involving damp-heat toxin.
  • The herbs in these prescriptions exhibit heat-clearing, detoxifying, anti-inflammatory, and wind-damp dispelling properties.
  • The analysis highlights a concentrated drug use pattern reflecting clear therapeutic principles in Tibetan medicine.