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Updated: Feb 18, 2026

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Oxidatively rearranged cycloartane triterpenoids from the seeds of Pseudolarix amabilis
Hui Guo1, Shen Yao1, Xinyi Yang1
1a College of Pharmaceutical Science , Zhejiang University of Technology , Hangzhou , P.R. China.
Abstract:
One novel and eight known oxidatively rearranged cycloartane triterpenoids were isolated from the seeds of Pseudolarix amabilis. The structure of the new isolate was elucidated on extensive spectroscopic analyses. Results indicated that pseudolarolide Q (4) exhibited strong antimicrobial activity against Gram-positive Staphylococcus aureus and Candida albicans at the MICs of 6.08 and 24.32 μM, respectively. Pseudolarolide I (2) showed the 11β-HSD1 inhibitory property at the IC50 value of 34.5 nM.
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