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Related Experiment Videos

Dysplastic naevi in a population-based survey.

K R Cooke1, G F Spears, D E Elder

  • 1Department of Preventive and Social Medicine, University of Otago Medical School, Dunedin, New Zealand.

Cancer
|March 15, 1989
PubMed
Summary

Dysplastic naevi, or atypical moles, are common in adults aged 30-59. Having numerous common moles significantly increases the risk of developing dysplastic naevi.

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Area of Science:

  • Dermatology
  • Epidemiology

Background:

  • Dysplastic naevi (DN) are clinically atypical moles.
  • Assessing the prevalence of DN in specific populations is crucial for understanding melanoma risk.

Purpose of the Study:

  • To determine the prevalence of dysplastic naevi in a non-Maori population in Milton, New Zealand.
  • To investigate the association between common mole counts and the presence of dysplastic naevi.

Main Methods:

  • A population-based survey was conducted on 380 non-Maori individuals aged 30-39 and 50-59.
  • Photographs of pigmented naevi (≥4 mm diameter) were taken and evaluated by two reviewers.
  • Interobserver agreement was assessed using kappa statistics.

Main Results:

  • Nine percent of participants had one or more dysplastic naevi (95% CI, 6%-13%).
  • Interobserver agreement for DN diagnosis was 85% (kappa = 0.55).
  • Individuals with 50 or more common moles (≥2 mm diameter) had a 40-fold increased likelihood of having three or more dysplastic naevi.

Conclusions:

  • Dysplastic naevi are relatively common in this population group.
  • A high count of common moles is a significant risk factor for the presence of dysplastic naevi.

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