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Updated: Jan 1, 2026

A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat
Published on: June 29, 2021
The Natural History of Degenerative Cervical Myelopathy
Jetan H Badhiwala1, Jefferson R Wilson1
1Division of Neurosurgery, Department of Surgery, St. Michael's Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada.
Abstract:
Despite being the leading cause of spinal cord dysfunction among adults worldwide, little is known about the natural history of degenerative cervical myelopathy (DCM). There is mounting evidence of the effectiveness of surgery for DCM in halting progression of symptoms, and in fact, in improving neurologic outcomes, functional status, and quality of life. However, surgical decision making relies on a weighing of the risks and benefits of alternative strategies. We reviewed the available literature pertaining to the natural course of DCM and the predictors of outcome of nonoperative approaches.

