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Updated: Feb 18, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody mAb by Neutralizing TNF Using an In Vitro Bioanalytical Method
16:07

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody mAb by Neutralizing TNF Using an In Vitro Bioanalytical Method

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Three cases of anti-TNF induced myositis and literature review

Orhan Zengin1, Mustafa Erkut Onder1, Samet Alkan2

  • 1Gaziantep University, School of Medicine, Department of Rheumatology, Gaziantep, Turkey.

Revista Brasileira De Reumatologia
|November 28, 2017
PubMed

Insights

Anti-tumor necrosis factor (TNF) drugs can rarely cause myositis, a muscle inflammation condition. Patients undergoing TNF inhibitor therapy for inflammatory diseases require careful monitoring for this rare side effect.

Area of Science:

  • Rheumatology
  • Immunology
  • Neurology

Background:

  • Anti-tumor necrosis factor (TNF) drugs are mainstays in treating inflammatory and rheumatologic diseases.
  • Myositis is a rare but serious adverse event associated with anti-TNF therapy.
Keywords:
Anti-tumor necrosis factor (anti-TNF) drugsFármacos antifator de necrose tumoral (anti-TNF)Jo-1MiositeMyositis

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