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Updated: Feb 18, 2026

Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
Two-dimensional vs 3-dimensional comparison of alveolar bone over maxillary incisors with A-point as a reference
Theodore J Kula1, Ahmed Ghoneima1, George Eckert2
1Department of Orthodontics and Oral Facial Genetics, School of Dentistry, Indiana University, Indianapolis, Ind.
Introduction:
Our objectives were to compare, relative to A-point, (1) bone thickness over the most forward maxillary incisor (MFMI) in 2 dimensions vs 3 dimensions, and (2) bone thickness and inclination of each maxillary incisor in 3 dimensions.
Methods:
Thirty-four cone-beam computed tomography (CBCT) images were coded, and 2-dimensional (2D) cephalograms were derived from each image using Dolphin software (Dolphin Imaging and Management Solutions, Chatsworth, Calif). A-point and the MFMI crown were located. After reliability tests, alveolar bone buccal to 3 points on the MFMI root, bone to reference line Frankfort horizontal (FH)-A-point, and incisor inclination were measured. This procedure was repeated on the 3-dimensional (3D) CBCT images comparing MFMI with all maxillary incisors. The 2D and 3D measurements were compared using paired t tests, and 3D measurements were compared with analysis of variance. A 5% significance level was used for all tests.
Results:
The MFMI's buccal bone thickness at the root apices and the distance between buccal bone and FH-A-point line at 2 root points were significantly greater in 2 dimensions than in 3 dimensions. In 3 dimensions, bone thickness at MFMI's root apex and the distance from FH-A-point line at all root points were significantly greater than those of the lateral incisors. Bone buccal to MFMI was significantly smaller than at the lateral incisors 3 mm from the cementoenamel junction.
Conclusions:
Evaluation of 2D CBCT derivations can result in overestimation of alveolar bone buccal to the maxillary incisor root apices compared with 3D evaluations. The anterior nasal spine obscures bone measurements over the maxillary incisors in 2 dimensions.

