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Brunner's gland hamartoma associated with microcarcinoids
T Matsui1, M Iida, M Fujischima
1Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Endoscopy
|January 1, 1989
Summary
A rare duodenal tumor, a Brunner's gland adenoma, was found in a 51-year-old female. This adenoma contained two microcarcinoid foci, a unique finding not previously documented in medical literature.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Brunner's glands are found in the duodenum and can develop benign or malignant tumors.
- Brunner's gland adenomas are rare, typically presenting as benign polyps.
- The presence of neuroendocrine cells (carcinoids) within these adenomas is exceptionally uncommon.
Observation:
- A pedunculated duodenal tumor was identified in a 51-year-old female patient.
- The tumor was covered by normal duodenal mucosa, obscuring its nature on initial inspection.
- Endoscopic resection was performed for diagnosis and treatment.
Findings:
- Histological examination confirmed the tumor as a Brunner's gland adenoma.
- Two distinct foci of microcarcinoids were identified within the adenoma.
- This combination of Brunner's gland adenoma with microcarcinoid components is novel.
Implications:
- This case expands the known histopathological spectrum of Brunner's gland adenomas.
- Highlights the importance of thorough histological evaluation of duodenal tumors, even those appearing benign.
- Suggests potential for neuroendocrine differentiation within these rare duodenal neoplasms.