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Photobiomodulation effect on children's scars
Jehan Alsharnoubi1, Omnia Mohamed2, Mary Fawzy3
1Pediatrics Department, National Institute of Laser Enhanced Sciences (N.I.L.E.S), Cairo University, House 2 Street 6 Zahraa Helwan, Cairo, Egypt. broncojena@gmail.com.
Insights
Low-level laser therapy (LLLT) significantly improves pediatric burn scars. This photobiomodulation treatment, combined with topical care, offers a safe and cost-effective option for hypertrophic scars in children.
Area of Science:
- Dermatology
- Pediatric Care
- Regenerative Medicine
Background:
- Burn scar management presents significant clinical and economic challenges, particularly in developing nations.
- There is a need for cost-effective therapeutic strategies for pediatric burn scars.
Purpose of the Study:
- To evaluate the efficacy of low-level laser therapy (LLLT) as an adjunct treatment for post-burn scar tissue in children.
- To compare LLLT combined with topical treatment against topical treatment alone.
Main Methods:
- A randomized controlled trial involving 15 children (ages 2-10) with burn scars.
- Scars were treated with either LLLT plus topical treatment (study area) or topical treatment alone (control area).
- Evaluations included Vancouver Scar Scale (VSS), ultrasonography (U/S), and laser Doppler perfusion imaging over 3 months.
Main Results:
- Significant improvements in scar appearance and tissue characteristics were observed in the LLLT-treated areas (P=0.005 for VSS, P=0.0001 for U/S).
- No significant difference in scar blood perfusion was detected between the study and control areas (P=0.18).
- No adverse effects were reported during the study period.
Conclusions:
- Photobiomodulation (LLLT) is an effective and safe therapeutic option for pediatric hypertrophic burn scars.
- LLLT should be considered as part of a combination therapy approach to enhance burn scar treatment outcomes in children.
Abstract:
The management of burn scars has become one of the major clinical challenges in the developing countries which involve enormous treatment cost; this needs new methods for better cost benefit relationship. The objective of the study is to analyze the effectiveness of low-level laser therapy on post-burn scar tissue in children. A randomized controlled study included 15 children, ranging from 2 to 10 years of age, presenting with burn scars. They received diode laser and topical treatment. Each scar was divided into two halves. One half was treated with laser therapy and topical treatment (study area), and the other half was treated with topical treatment only (control area). The children were evaluated before and after 3 months of the study by Vancouver Scar Scale (VSS), ultrasonography (U/S), and laser Doppler perfusion imaging. Significant improvement was reported in the studied area compared to the control area for patients with P values (P = 0.005) and (P = 0.0001) for VSS and U/S scores, respectively. No difference was detected for blood perfusion to the scar between both areas (P = 0.18). In addition, no adverse effect was reported. Photobiomodulation is an efficient and safe therapeutic modality for post-burn hypertrophic scars in children and should be considered a part of combination therapy for better results.
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