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[Iodinated contrast-induced encephalopathy: a pathology that must be borne in mind when carrying out endovascular
M I Morales-Casado1, F Munoz-Escudero2, J M Garcia-Benassi1
1Hospital Virgen de la Salud, 45005 Toledo, Espana.
Insights
Neurotoxicity from contrast media is a rare complication of endovascular procedures. Prompt diagnosis and treatment lead to excellent outcomes, with symptoms typically resolving within 72 hours.
Area of Science:
- Neurology
- Radiology
- Cardiovascular Medicine
Background:
- Endovascular procedures for cardiovascular and cerebrovascular diseases are increasing.
- A rare complication is contrast-induced neurotoxicity, requiring high clinical suspicion for diagnosis.
Observation:
- A 61-year-old male experienced an epileptic attack and left-hemisphere deficit post-arteriography.
- Vascular pathology was excluded; MRI confirmed contrast-induced encephalopathy.
- Symptoms resolved within 72 hours with corticosteroid therapy.
Findings:
- Contrast-induced encephalopathy presents with diverse neurological symptoms.
- The condition is typically self-limiting, resolving within 24-72 hours.
- Neuronal damage can occur following contrast agent administration.
Implications:
- Early recognition of contrast-induced encephalopathy is vital for effective management.
- The prognosis for contrast-induced encephalopathy is generally excellent.
- This case highlights the importance of considering contrast neurotoxicity in post-procedural neurological deficits.
Introduction:
In recent years there has been an increase in the number of endovascular examinations in the study of both cardiovascular and cerebrovascular diseases. One very infrequent complication is neurotoxicity due to contrast, and it must be suspected within the context of a neurological deficit following such examinations in order to be able to diagnose it.
Case Report:
A 61-year-old male who presented an epileptic attack and later deficit in the left hemisphere following diagnostic arteriography. After ruling out the possibility of an urgent vascular pathology, he was submitted to a magnetic resonance brain scan with the suspicion of this condition. The clinical signs and symptoms were limited to 72 hours with cortisone therapy.
Conclusions:
Contrast-induced encephalopathy covers a wide range of clinical features which, in the vast majority of cases, are self-limiting to 24-72 hours, and within the context of neuronal damage following contrast infusion. Its prognosis is excellent, and diagnostic suspicion is crucial in its treatment.
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