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Updated: Feb 18, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase

Chin Piow Wong1, Takayoshi Awakawa1, Yu Nakashima1

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Angewandte Chemie (International Ed. in English)
|November 28, 2017
PubMed

Keywords:
alkaloidsbiosynthesisenzyme mechanismsprenylationprenyltransferases

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