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Related Concept Videos

Mortar Properties01:17

Mortar Properties

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Mortar properties encompass a range of characteristics crucial for construction and masonry work, including workability, water retention, bond strength, durability, compressive strength, volume change, and appearance. Workability refers to mortar's ability to be easily applied and manipulated without sagging or falling off surfaces, which is important for efficient masonry unit placement and alignment. Water retention is essential to prevent the mortar from losing moisture too quickly to...
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The bond between aggregate particles and the cement matrix is significantly influenced by the shape and surface texture of the aggregates. High-strength concretes benefit from a rougher texture, which leads to stronger bonding due to greater adhesion. Angular aggregates with larger surface areas also enhance this bond. The bonding quality, however, is complex to assess as no universally accepted test exists. Good bonding is indicated when a crushed concrete specimen shows some aggregate...
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Cross-linking effect on dentin bond strength and MMPs activity.

Annalisa Mazzoni1, Valeria Angeloni2, Allegra Comba1

  • 1Department of Biomedical and Neuromotor Sciences, DIBINEM, University of Bologna - Alma Mater Studiorum, Bologna, Italy.

Dental Materials : Official Publication of the Academy of Dental Materials
|November 29, 2017
PubMed
Summary

1-ethyl-3 (3-dimethylaminopropyl) carbodiimide (EDC) improves long-term dental adhesive bond strength and stabilizes interfaces. EDC also significantly reduces dentinal MMPs activity, regardless of the adhesive system used.

Keywords:
Dentin bonding systemsEDCMMPsProtein cross-linkers

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Area of Science:

  • Dental Materials Science
  • Biomaterials Engineering
  • Adhesive Dentistry

Background:

  • Dental adhesives are crucial for restoring tooth structure.
  • Dentin matrix metalloproteinases (MMPs) can degrade the hybrid layer, compromising bond durability.
  • 1-ethyl-3 (3-dimethylaminopropyl) carbodiimide (EDC) is explored for its potential to inhibit MMPs and enhance adhesive performance.

Purpose of the Study:

  • To evaluate the efficacy of an EDC-containing primer in improving immediate and long-term bond strength of self-etch and etch-and-rinse adhesives.
  • To assess the effect of EDC on dentinal MMPs activity.
  • To determine if EDC's effects are adhesive-system-dependent.

Main Methods:

  • Microtensile bond strength (μTBS) tests were performed on 80 molars immediately and after 1-year aging.
  • Groups included Clearfil SE (CSE) and XP Bond (XPB) with and without EDC pre-treatment.
  • Gelatin zymography was used to analyze dentinal MMPs activity.

Main Results:

  • EDC pre-treatment did not affect immediate bond strength but significantly improved it after 1-year aging for both adhesive systems.
  • EDC pre-treatment with CSE resulted in incomplete MMPs inactivation.
  • EDC pre-treatment with XPB led to almost complete inactivation of dentinal gelatinases.

Conclusions:

  • EDC enhances the long-term stability of dental adhesive interfaces.
  • EDC demonstrates efficacy in reducing dentinal MMPs activity, with varying degrees of inactivation depending on the adhesive system.
  • The observed changes in the dentin matrix by EDC are independent of the specific adhesive system used.