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Combination of MALDI-TOF MS and PBP2' latex agglutination assay for rapid MRSA detection

Marianna Ábrók1, Andrea Lázár1, Mária Szécsényi1

  • 1Institute of Clinical Microbiology, University of Szeged, Szeged, Hungary.

Journal of Microbiological Methods
|November 29, 2017
PubMed

Keywords:
Latex agglutination testMethicillin-resistant Staphylococcus aureusPenicillin-binding protein 2′Salt-containing trypticase soy brothSample preparationScreening

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Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
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