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Associations between coronary artery disease, aneurysm and ectasia
Cengiz Ovalı1, Baktash Morrad2
1Cardiovascular Surgery Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Insights
Coronary artery aneurysms (CAA) were more frequent in patients with coronary artery disease (CAD), while coronary artery ectasia (CAE) showed no significant difference. Further research is needed for CAA and CAE treatment and prognosis.
Area of Science:
- Cardiology
- Vascular Medicine
- Diagnostic Imaging
Background:
- Coronary artery aneurysm (CAA) and ectasia (CAE) are vascular conditions that can occur alongside coronary artery disease (CAD).
- Understanding the prevalence and association of CAA and CAE with CAD is crucial for patient management.
Purpose of the Study:
- To investigate the frequency and contribution of coronary artery aneurysm/ectasia.
- To determine the correlation between CAA/CAE and coronary artery disease (CAD).
Main Methods:
- Retrospective analysis of 418 adult patients' coronary angiography records.
- CAD defined as >50% stenosis in epicardial coronary arteries.
- Comparison of CAA/CAE prevalence and features in patients with and without CAD.
Main Results:
- CAA/CAE observed in 6.6% of CAD+ and 6.1% of CAD- patients (p=0.2).
- Coronary artery aneurysms were significantly higher in CAD+ patients (0.8% vs. 0.4%, p=0.015).
- Coronary artery ectasia showed no significant variation between CAD+ and CAD- groups (5.8% vs. 5.7%, p=0.47).
Conclusions:
- CAA and CAE are frequently encountered in patients undergoing angiography.
- CAA and CAE are not merely simple vessel dilations and require further investigation.
- Additional studies are necessary to establish effective treatments and prognostic evaluations for CAA/CAE.
Aim:
Investigation the frequency and contribution of coronary artery aneurysm/ectasia in addition to their correlation with coronary artery disease (CAD).
Material And Methods:
We retrospectively evaluated the coronary angiography records of 6500 adult consecutive patients, and 418 of them were met inclusion criteria and used in the present study. The CAD was defined as the presence of angiographic coronary stenosis of > 50% of the luminal diameter in no less than one of the epicardial coronary arteries. Moreover, the prevalence and features of the coronary artery aneurysm/ectasia among the cases with and without CAD were compared.
Results:
We observed coronary artery aneurysm (CAA) and ectasia (CAE) in 6.6% of the patients with significant CAD (+), and 6.1% of the patients with significant CAD (-) (p = 0.2). The percentage of coronary artery aneurysms was significantly higher in CAD (+) patients than in CAD (-) patients (0.8% vs. 0.4%, p = 0.015). The percentage of coronary artery ectasia showed no variation between CAD (+) patients and CAD (-) patients (5.8% vs. 5.7%, p = 0.47). The frequency of spotting aneurysm on a single coronary artery was higher than discerning aneurysm on two or three coronary arteries.
Conclusions:
Presence of CAA or CAE cases is often encountered in those who have undergone angiography procedures. Furthermore, CAA and CAE should not be considered as simple dilations of vessels. Further studies are needed to determine the effective procedures for the treatment and prognostic evaluations of the patients with CAA or CAE.
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