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Clinical features, management and mortality in diabetic and non-diabetic patients with heart failure - observations

Łukasz Siedlecki1, Bożena Szyguła-Jurkiewicz1, Łukasz Pyka2

  • 13 Department of Cardiology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.

Kardiochirurgia I Torakochirurgia Polska = Polish Journal of Cardio-Thoracic Surgery
|November 29, 2017
PubMed

Insights

Diabetes mellitus (DM) significantly increases mortality risk in heart failure (HF) patients. This study found 42.6% of hospitalized HF patients had DM, with higher death rates observed in those with diabetes.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Diabetes mellitus (DM) and heart failure (HF) frequently coexist, impacting patient outcomes.
  • Understanding the interplay between these conditions is crucial for effective clinical management.

Purpose of the Study:

  • To investigate the clinical profiles, management approaches, and 3-year mortality rates in hospitalized heart failure patients with and without diabetes.
  • To assess the impact of diabetes on heart failure patient outcomes within a specialized cardiology center.

Main Methods:

  • Analysis of prospective data from the COMMIT-HF registry, including 1397 patients with symptomatic chronic systolic heart failure (LVEF < 35%).
  • Inclusion of demographic, clinical characteristics, medical history, and inpatient therapies.
  • 3-year follow-up using national health-care provider data.

Main Results:

  • 42.6% of analyzed heart failure patients had diabetes (595/1397).
  • Diabetic patients exhibited higher comorbidity rates.
  • 3-year mortality was significantly higher in diabetic patients (33.4%) compared to non-diabetic patients (20.3%), p < 0.0001.

Conclusions:

  • Diabetes mellitus is highly prevalent (42.6%) in hospitalized heart failure patients.
  • Diabetes negatively affects renal function and heart failure symptoms.
  • Diabetes is independently associated with increased mortality in heart failure patients, despite advancements in treatment.
Abstract

Keywords:
diabetes mellitusheart failureregistry

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