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Decrease in toe pinch force in male type 2 diabetic patients with diabetic nephropathy.

Hiroaki Kataoka1,2, Nobuyuki Miyatake3, Naomi Kitayama4

  • 1Rehabilitation Center, KKR Takamatsu Hospital, 4-18, Tenjinmae, Takamatsu-city, Kagawa, 760-0018, Japan. h.kataoka59@gmail.com.

Clinical and Experimental Nephrology
|November 29, 2017
PubMed
Summary
This summary is machine-generated.

Diabetic nephropathy reduces toe pinch force (TPF) and knee extension force (KEF) in men with type 2 diabetes. Diabetic polyneuropathy (DPN) and disease progression are key factors influencing these strength declines.

Keywords:
Diabetic nephropathyToe pinch forceType 2 diabetes mellitus

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Area of Science:

  • Endocrinology
  • Nephrology
  • Neurology

Background:

  • Diabetic nephropathy is a common complication of type 2 diabetes.
  • Muscle strength deficits, including toe pinch force (TPF), are increasingly recognized in diabetic patients.

Purpose of the Study:

  • To investigate the toe pinch force (TPF) in type 2 diabetic patients with diabetic nephropathy.
  • To analyze TPF and knee extension force (KEF) across different stages of diabetic nephropathy.
  • To identify factors influencing TPF and KEF in this population.

Main Methods:

  • Cross-sectional study of 74 men with diabetic nephropathy.
  • Comparison of TPF and KEF among normoalbuminuria, microalbuminuria, and overt nephropathy groups.
  • Multiple regression analysis to determine factors affecting TPF and KEF.

Main Results:

  • TPF was significantly lower in the overt nephropathy group compared to normoalbuminuria and microalbuminuria groups.
  • KEF was significantly lower in the overt nephropathy group compared to the normoalbuminuria group.
  • Diabetic polyneuropathy (DPN) and diabetic nephropathy were significant predictors of TPF; age, BMI, and diabetic nephropathy predicted KEF.

Conclusions:

  • TPF and KEF decrease with the progression of diabetic nephropathy in men with type 2 diabetes.
  • Diabetic nephropathy and DPN are critical factors contributing to reduced muscle strength.
  • Findings highlight the impact of nephropathy and neuropathy on physical function in diabetic patients.