Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

60.3K
Overview
60.3K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

4.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.4K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

344
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
344
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

1.6K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.6K
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

1.1K
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
1.1K
Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

1.4K
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Venous Thromboembolism Risk and Prevention After Gastrointestinal Cancer Surgery: Real World Evidence From a Large Integrated Healthcare System.

Journal of surgical oncology·2026
Same author

Glycemic Control and Utilization Risk With the Conversion of Glimepiride to Glipizide in Adults 64 Years and Older at an Integrated Health Care System.

Journal of the American Geriatrics Society·2026
Same author

Loneliness and Social Isolation Up to 5 Years after Bariatric Surgery in the Bariatric Experience Long Term (BELONG) Study.

Obesity surgery·2026
Same author

The Coming Age of Interdependence.

The journal of applied laboratory medicine·2026
Same author

Sociodemographic differences in clinical phenotypes among patients with COPD: a latent class analysis.

BMJ open respiratory research·2026
Same author

Socioeconomic Factors Associated with Receipt of Minimally Invasive Surgery for NSCLC: Evidence from the National Cancer Database.

Cancers·2026

Related Experiment Video

Updated: Feb 18, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.5K

Improving antibiotic stewardship: a stepped-wedge cluster randomized trial.

Adam L Sharp1, Yi R Hu, Ernest Shen

  • 1Kaiser Permanente Southern California, 100 S Los Robles Ave, 2nd Fl, Pasadena, CA 91101.

The American Journal of Managed Care
|November 29, 2017
PubMed
Summary

Clinical decision support (CDS) and provider education improved antibiotic stewardship for acute sinusitis. While education

More Related Videos

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
11:15

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations

Published on: July 24, 2021

5.5K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

27.8K

Related Experiment Videos

Last Updated: Feb 18, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.5K
Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
11:15

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations

Published on: July 24, 2021

5.5K
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
12:03

Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method

Published on: April 18, 2019

27.8K

Area of Science:

  • Infectious Diseases
  • Health Services Research
  • Medical Education

Background:

  • Antibiotic stewardship is crucial for optimizing patient outcomes and healthcare costs.
  • Acute sinusitis management often involves antibiotic prescribing, necessitating effective interventions to ensure appropriate use.
  • Provider experience may influence antibiotic prescribing patterns for upper respiratory infections.

Purpose of the Study:

  • To evaluate the impact of provider education and clinical decision support (CDS) on antibiotic prescribing for acute sinusitis.
  • To assess how provider experience moderates the effect of CDS on antibiotic prescribing.
  • To analyze changes in diagnosis patterns and guideline-concordant antibiotic use.

Main Methods:

  • A stepped-wedge cluster randomized trial involving 126 clinics.
  • Intervention included provider education and CDS implementation.
  • Analysis of 21,949 encounters, with secondary chart review for guideline concordance.

Main Results:

  • CDS significantly reduced antibiotic prescriptions for acute sinusitis (AOR, 0.78).
  • Provider education showed an initial significant reduction (AOR, 0.51) but the effect was not sustained.
  • Guideline-concordant antibiotic use increased by 14%; CDS effectiveness varied by medical center.

Conclusions:

  • Provider education and CDS interventions enhance antibiotic stewardship for acute sinusitis.
  • The benefits of provider education were transient, while CDS demonstrated a modest but persistent effect.
  • CDS effectiveness varied across different clinical settings, highlighting the need for tailored implementation strategies.