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Adherence to Methodological Standards in Research Using the National Inpatient Sample
Rohan Khera1, Suveen Angraal2, Tyler Couch1
1Division of Cardiology, University of Texas Southwestern Medical Center, Dallas.
Most studies using the National Inpatient Sample (NIS) database did not follow required research practices. This highlights a need for improved data analysis and interpretation strategies for public health research.
Area of Science:
- Health Services Research
- Public Health Data Analytics
- Biostatistics
Background:
- Publicly available datasets like the National Inpatient Sample (NIS) offer valuable research opportunities.
- However, their unique structure necessitates specific analytical approaches for accurate interpretation.
- Adherence to recommended research practices is crucial for the validity of findings derived from such data.
Purpose of the Study:
- To evaluate the adherence to essential research practices among studies utilizing the National Inpatient Sample (NIS) database.
- To identify common deviations from recommended methodologies in NIS research.
- To inform strategies for enhancing the quality of research using large public health datasets.
Main Methods:
- An observational study systematically reviewed 120 publications from January 2015 to December 2016 that used the NIS.
- Studies were assessed for adherence to 7 key research practices recommended by the Agency for Healthcare Research and Quality (AHRQ).
- Practices covered data interpretation, research design, and data analysis, including accounting for survey design and data structure changes.
Main Results:
- A significant majority of reviewed studies (85%) failed to adhere to at least one required practice.
- 62% of studies deviated from two or more essential research practices.
- Common issues included misinterpreting hospitalizations as unique patients, inappropriate state-level analyses, and failing to account for the NIS complex survey design and data structure changes.
Conclusions:
- The majority of recent publications using the NIS database did not comply with required research practices.
- There is a critical need to develop and implement strategies to improve the quality and rigor of research conducted with the NIS.
- Findings suggest potential similar issues in the utilization of other large, publicly available health datasets, warranting further investigation.
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