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Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Optical Coherence Tomography and Subclinical Optical Neuritis in Longitudinally Extensive Transverse Myelitis
Prakash Kumar Sinha1, Deepika Joshi1, Virendra Pratap Singh2
1Department of Neurology, IMS, BHU, Varanasi, Uttar Pradesh, India.
Objective:
The aim is to compare the retinal nerve fiber layer (RNFL) thickness of longitudinally extensive transverse myelitis (LETM) eyes without previous optic neuritis with that of healthy control subjects.
Methods:
Over 20 LETM eyes and 20 normal control eyes were included in the study and subjected to optical coherence tomography to evaluate and compare the RNFL thickness.
Result:
Significant RNFL thinning was observed at 8 o'clock position in LETM eyes as compared to the control eyes (P = 0.038). No significant differences were seen in other RNFL measurements.
Conclusion:
Even in the absence of previous optic neuritis LETM can lead to subclinical axonal damage leading to focal RNFL thinning.
