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Effect of Femtosecond Laser-Assisted Cataract Surgery (FLACS) on Endothelial Cell Count
Muhammad Saim Khan1, Asad Habib1, Mazhar Ishaq1
1Department of Ophthalmology, Armed Forces Institute of Ophthalmology, Rawalpindi.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|November 30, 2017
Summary
Femtosecond laser-assisted cataract surgery (FLACS) causes significantly less endothelial cell loss than conventional phacoemulsification. This study shows FLACS is a safe and effective cataract treatment option.
Area of Science:
- Ophthalmology
- Surgical Innovation
- Corneal Health
Background:
- Cataract surgery is a common procedure to restore vision.
- Endothelial cell count is a critical indicator of corneal health post-surgery.
- Comparing surgical techniques is essential for patient outcomes.
Purpose of the Study:
- To compare endothelial cell count changes after femtosecond laser-assisted cataract surgery (FLACS) versus conventional phacoemulsification.
- To evaluate the safety and efficacy of FLACS in cataract treatment.
Main Methods:
- A randomized controlled clinical trial was conducted.
- Patients with senile cataract (age 40-80) were included; specific exclusions applied.
- Endothelial cell count was measured pre- and post-surgery (4 weeks) using specular microscopy.
Main Results:
- Fifty eyes (25 per group) underwent surgery.
- Femtosecond laser-assisted cataract surgery (FLACS) resulted in significantly less endothelial cell loss (median change 23) compared to conventional phacoemulsification (median change 228).
- Statistical significance was confirmed (p<0.05, Mann Whitney U-test).
Conclusions:
- Femtosecond laser-assisted cataract surgery (FLACS) is a safe and effective cataract treatment.
- FLACS induces significantly less endothelial cell loss than conventional phacoemulsification.
- FLACS offers a potential advantage in preserving corneal health.

