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Updated: Feb 17, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Transient Methemoglobinemia in three Neonates due to Maternal Pudendal Anesthesia
Sara Erol1, Zehra Arslan1, Isemi Han Celik1
1Department of Neonatal Intensive Care Unit Etlik Zubeyde Hanim Women's Health Education and Research Hospital Ankara Turkey.
Abstract:
Methemoglobin (MetHb) is a form of hemoglobin which contains iron in ferric state. The delivery of oxygen to tissues is impaired and cellular hypoxia develops with an increase in MetHb levels. Methemoglobinemia is a rare but potentially lethal complication of local anesthetics. In this clinical brief, three cases of transient neonatal methemoglobinemia, caused by maternal pudendal anesthesia with prilocaine, are reported.
Insights
Transient neonatal methemoglobinemia can occur after maternal use of prilocaine anesthesia. This condition impairs oxygen delivery, potentially causing cellular hypoxia. Prompt recognition and management are crucial for infant well-being.
Area of Science:
- Anesthesiology
- Neonatology
- Hematology
Background:
- Methemoglobin (MetHb) is a hemoglobin form with ferric iron, impairing oxygen transport.
- Elevated MetHb levels can lead to tissue hypoxia and cellular damage.
- Methemoglobinemia is a rare but serious complication associated with local anesthetics.
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