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Updated: Feb 17, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Movement disorders and chronic psychosis: Five new things
Davide Martino1, Francesca Morgante1
1Movement Disorders Program (DM), Department of Clinical Neurosciences, University of Calgary, Canada; Department of Clinical and Experimental Medicine (FM), University of Messina, Italy; and Institute of Molecular and Clinical Sciences (FM), St George's University of London, UK.
Antipsychotic medications can cause movement disorders like parkinsonism and tardive dyskinesia. Early detection and monitoring are crucial for managing these side effects in patients with chronic psychosis.
Area of Science:
- Psychiatry
- Neurology
Background:
- Movement disorders are a significant concern in patients with chronic psychosis.
- Antipsychotic medications, particularly newer generations, are associated with hyperkinetic and hypokinetic movement disorders.
Purpose of the Study:
- To review recent research (2014-2016) on movement disorders in psychosis.
- To identify clinically relevant messages regarding hyperkinetic and hypokinetic movement disorders.
Main Methods:
- Literature review of peer-reviewed articles.
- Synthesis of findings from population-based studies and clinical trials.
Main Results:
- Antipsychotic use increases the risk of extrapyramidal symptoms.
- Dopamine transporter imaging may identify progressive antipsychotic-induced parkinsonism.
- VMAT-2 inhibitors and deep brain stimulation show promise for tardive dyskinesia.
- Hyperkinesias can be early predictors of psychosis in youth.
Conclusions:
- Movement disorders linked to new-generation antipsychotics are common.
- Enhanced monitoring is necessary to assess the impact on patients' quality of life.
- Preventing underascertainment of these movement disorders is essential.
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