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Total prostatectomy for clinically localized prostatic cancer: long-term results.
R P Gibbons1, R J Correa, G E Brannen
1Section of Urology and Renal Transplantation, Virginia Mason Clinic, Seattle, Washington.
The Journal of Urology
|March 1, 1989
Summary
Total perineal prostatectomy for localized prostate cancer shows a 15-year cause-specific survival of 90%. This radical prostatectomy approach offers durable long-term disease control without adjuvant therapy.
Area of Science:
- Urology
- Oncology
- Surgical Oncology
Background:
- Radical prostatectomy is a primary treatment for localized prostate cancer.
- Long-term outcomes data for specific surgical approaches are crucial for treatment planning.
Purpose of the Study:
- To evaluate the long-term oncological outcomes of total perineal prostatectomy.
- To assess the disease impact of this surgical technique over a 15-year follow-up period.
Main Methods:
- Retrospective review of the first 52 patients with clinically localized prostate cancer.
- Patients underwent total perineal prostatectomy without adjuvant therapy.
- Minimum follow-up of 15 years.
Main Results:
- Nine patients (17%) experienced disease recurrence.
- Five patients (10%) died of prostate cancer.
- Observed overall survival at 15 years was 64%.
- Actuarial survival at 15 years was 67%.
- Cause-specific survival at 15 years was 90%.
Conclusions:
- Total perineal prostatectomy provides significant long-term survival benefits for localized prostate cancer.
- The procedure demonstrates a favorable cause-specific survival rate even without adjuvant treatments.
- This surgical approach is a viable option for managing localized prostate cancer with durable results.