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Updated: Feb 17, 2026

Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser
Published on: May 5, 2020
[Comparative analysis of the effectiveness of various techniques of endoscopic prostate enucleation in a single
D V Enikeev1, P V Glybochko1, Yu G Alyaev1
1Sechenov First Moscow State Medical University of the Russian Healthcare Ministry, Research Institute of Uronephrology and Human Reproductive Health, Moscow, Russia.
Aim:
To compare electro- and laser enucleation (thulium, holmium) of prostate hyperplasia.
Material And Methods:
693 prostate hyperplasia patients were enrolled. 489 patients underwent holmium enucleation (HoLEP), 51 - monopolar enucleation, 153 - thulium enucleation (ThuLEP). Prostate volume was 91.7 (50-250) cm3. There were no significant differences in preoperative variables between both groups (I-PSS, QoL, Qmax, residual urine volume) (p>0.05).
Results:
Mean time of HoLEP was 97.0±42.2 min, monopolar enucleation - 112.9±36.3 min, ThuLEP duration was significantly less (77.4±36.3 min, p<0.01). An efficacy of all methods was confirmed in 6 months after surgery by significant (p<0.01) improvement of functional parameters (I-PSS, QoL, Qmax, residual urine volume).
Conclusion:
High efficiency of thulium and holmium enucleation allows to consider them as 'gold standard' of prostate hyperplasia management. Despite higher incidence of complications an efficacy of monopolar enucleation is comparable to that in laser techniques.

