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Identifying simultaneous rearrangements in cancer genomes

Layla Oesper1, Simone Dantas2, Benjamin J Raphael3

  • 1Department of Computer Science, Carleton College, Northfield, MN, USA.

Bioinformatics (Oxford, England)
|November 30, 2017
PubMed
Summary

Cancer genomes may acquire mutations simultaneously through catastrophic events like chromothripsis. We introduce the H/T alternating fraction, a new signature to identify simultaneous mutations in cancer evolution.

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