Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Congenital syphilis and necrotizing funisitis.

R M Fojaco1, G T Hensley, L Moskowitz

  • 1University of Miami/Jackson Memorial Medical Center, Department of Pathology, FL 33101.

JAMA
|March 24, 1989
PubMed
Summary

Necrotizing funisitis, an umbilical cord inflammation, was exclusively linked to syphilis in 16 cases over 5 years. This finding, supported by historical literature, aids in diagnosing congenital syphilis at birth via the "barberpole" cord appearance.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac disease and hypertension. Considerations for office treatment.

Dental clinics of North America·1999
Same author

Lightning strikes at a mass gathering.

Southern medical journal·1999
Same author

Consideration of adult critical care training for emergency physicians.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·1999
Same author

MR of Toxoplasma encephalitis: signal characteristics on T2-weighted images and pathologic correlation.

Journal of computer assisted tomography·1996
Same author

Psychological management of postsurgical pain and patient adherence.

Hand clinics·1996
Same author

Infections in children with human immunodeficiency virus/acquired immunodeficiency syndrome: an autopsy study of 30 cases in south Florida, 1990-1993.

Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association·1995

Area of Science:

  • Obstetrics and Gynecology
  • Neonatology
  • Infectious Diseases

Background:

  • Necrotizing funisitis is a deep inflammatory process affecting the umbilical cord matrix.
  • Previous understanding did not strongly associate this condition with specific infections.

Purpose of the Study:

  • To investigate the association between necrotizing funisitis and infectious agents.
  • To determine if necrotizing funisitis can serve as a diagnostic marker for congenital syphilis.

Main Methods:

  • Retrospective review of 16 cases of necrotizing funisitis over a 5-year period.
  • Analysis of associated maternal and congenital infections.
  • Comparison with historical medical literature on funisitis and syphilis.

Related Experiment Videos

Main Results:

  • All 16 identified cases of necrotizing funisitis were associated with maternal and congenital syphilis.
  • No other infections were found to be associated with necrotizing funisitis during the study period.
  • Historical literature confirms syphilis as a specific cause of deep funisitis with angiophlebitis.

Conclusions:

  • Necrotizing funisitis is strongly associated with syphilis, suggesting a specific etiological link.
  • The characteristic "barberpole" umbilical cord appearance in necrotizing funisitis can facilitate presumptive diagnosis of congenital syphilis at birth.