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Lipid Injectable Emulsions: Infusion Confusion.
Phil Ayers1, Joseph I Boullata2, Peggi Guenter3
1Mississippi Baptist Medical Center, Jackson, Mississippi, USA.
JPEN. Journal of Parenteral and Enteral Nutrition
|December 1, 2017
Summary
The commentary discusses the safe infusion duration for lipid injectable emulsions (ILEs). It highlights a discrepancy between current recommendations, suggesting up to 24 hours, and older guidelines not exceeding 12 hours.
Area of Science:
- Clinical Nutrition
- Parenteral Nutrition
- Infusion Therapy
Background:
- Lipid injectable emulsions (ILEs) are crucial components of parenteral nutrition.
- Established guidelines for ILE infusion duration have varied, causing clinical uncertainty.
- Recent discussions propose extended infusion times for separately administered ILEs.
Purpose of the Study:
- To address the debate surrounding the optimal infusion duration for lipid injectable emulsions (ILEs).
- To reconcile differing recommendations on ILE administration times.
- To clarify best practices for ILE infusion when not combined with amino acids and dextrose.
Main Methods:
- Review of current literature and guidelines on parenteral nutrition.
- Analysis of commentary regarding lipid injectable emulsion (ILE) infusion protocols.
- Comparison of recommended infusion times from different expert bodies.
Main Results:
- Mundi et al. suggest ILEs administered separately can be infused over up to 24 hours.
- Previous guidelines from the American Society for Parenteral and Enteral Nutrition recommended a maximum infusion time of 12 hours.
- A divergence in recommended practice for ILE infusion duration exists.
Conclusions:
- The commentary highlights a need for updated consensus on ILE infusion duration.
- Clarification is required regarding safe and effective administration times for lipid injectable emulsions.
- Further research may be needed to establish evidence-based recommendations for ILE infusion.
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