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Updated: Feb 16, 2026

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
Published on: July 10, 2018
[NMDA receptor and its role in cardiovascular diseases]
1Laboratory of Molecular Medicine, Second Affiliated Hospital, Nanchang University, Nanchang 330006, China.
Abstract:
Cardiovascular disease is the main threat to human health, which is one of the important causes of death in worldwide. N-methyl-D-aspartate receptor (NMDAR) is one of crucial ionic glutamate receptors. The physiology and pharmacology function of the composition of NMDAR are very complicated. Researches have shown that NMDAR with a high permeability to calcium and a unique feature of controlling numerous calcium-dependent processes. NMDAR affects the occurrence and development of cardiovascular disease such as hypertension, arrhythmia, myocardial infarction.
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