Pregnant hepatitis B carrier

Duodecim; Laaketieteellinen Aikakauskirja
|December 1, 2017
PubMed

While screening for viral hepatitides is not carried out among women of reproductive age in Finland, maternity clinics offer all pregnant women screening for hepatitis B during early pregnancy. A hepatitis B carrier should discuss the timing of pregnancy. In general, pregnancy does not influence the course of hepatitis B. The most significant route of transmission is still the perinatal one, from the mother to the newborn infant. The younger the age when the infection is contracted, the higher is the risk of it becoming chronic and complicated. The risk of transmission correlates with the mother's serum HBV-DNA level and also with HBeAg positivity. At the beginning of the third trimester tenofovir decreases the replication of the virus and prevents the newborn infant from infection.

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