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Lactotripeptides Supplementations Alleviate the Decrease in Maximal Isometric Force After High-Intensity Eccentric

Kaname Tagawa1, Song-Gyu Ra, Youngju Choi

  • 1From the Division of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan (KT); Sports Research and Development and Core, University of Tsukuba, Tsukuba, Japan (KT, YC); Faculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan (SGR); and Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, Japan (SM).

American Journal of Physical Medicine & Rehabilitation
|December 1, 2017
PubMed
Summary
This summary is machine-generated.

Lactotripeptides supplementation may help reduce muscle damage after eccentric exercise (ECC). This study found that lactotripeptides increased brachial arterial diameter, potentially alleviating the decrease in maximal isometric force following ECC.

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Area of Science:

  • Exercise Physiology
  • Nutritional Science
  • Muscle Physiology

Background:

  • Eccentric exercise (ECC) can lead to muscle damage, indicated by decreased maximal isometric force.
  • Understanding interventions to mitigate exercise-induced muscle damage is crucial for athletes and active individuals.

Purpose of the Study:

  • To investigate the effects of lactotripeptides supplementation on maximal isometric force after ECC.
  • To determine if lactotripeptides influence brachial arterial diameter, a potential indicator of muscle recovery.

Main Methods:

  • Twenty-two young men underwent 50 ECC of elbow flexors.
  • Subjects received either placebo or lactotripeptides (4.5 mg/d) over two days.
  • Maximal isometric force and brachial arterial diameter were measured pre- and post-exercise.

Main Results:

  • Maximal isometric force decreased significantly in both groups post-ECC.
  • Brachial arterial diameter significantly increased only in the lactotripeptides group.
  • Changes in maximal isometric force correlated with changes in brachial arterial diameter.

Conclusions:

  • Lactotripeptides supplementation appears to alleviate the reduction in maximal isometric force following ECC.
  • The mechanism may involve an increase in brachial arterial diameter induced by lactotripeptides.
  • These findings suggest a potential benefit of lactotripeptides for muscle recovery after strenuous exercise.