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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Chronic Pancreatitis II: Collaborative Care01:29

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
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Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
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Clinical Management: Resectable Disease.

Rebekah R White, Andrew M Lowy

    Cancer Journal (Sudbury, Mass.)
    |December 1, 2017
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    Summary
    This summary is machine-generated.

    Advances in systemic therapy and surgical care have improved survival for localized pancreatic cancer. Neoadjuvant therapy is increasingly used for borderline resectable tumors, potentially becoming the standard of care.

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    Area of Science:

    • Oncology
    • Surgical Oncology
    • Gastroenterology

    Background:

    • Pancreatic cancer cures remain elusive, with localized disease being the only curable form.
    • Survival for localized pancreatic cancer has improved due to advances in adjuvant therapy and perioperative care.
    • The definition and management of borderline resectable pancreatic cancers are evolving.

    Purpose of the Study:

    • To review recent advancements in the management of localized and borderline resectable pancreatic cancer.
    • To evaluate the role of neoadjuvant systemic therapy in pancreatic cancer treatment.
    • To hypothesize the future standard of care for resectable pancreatic cancer.

    Main Methods:

    • Analysis of outcome data from phase III adjuvant trials over the past decade.
    • Review of advancements in surgical techniques for borderline resectable tumors.
    • Assessment of the increasing use of systemic therapy in the neoadjuvant setting.

    Main Results:

    • Improved survival rates for localized pancreatic cancer patients.
    • Objective definition and ongoing study of borderline resectable pancreatic cancers.
    • Increased feasibility of surgery for previously inoperable tumors due to neoadjuvant therapy.

    Conclusions:

    • Neoadjuvant systemic therapy is becoming increasingly important in pancreatic cancer management.
    • Challenges exist in delivering postoperative systemic therapy.
    • The neoadjuvant setting may emerge as the standard of care for resectable pancreatic cancer.