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Association of IgA nephropathy and myasthenia gravis

M Miyazaki1, N Kimura, K Imai

  • 1Department of Internal Medicine, School of Medicine, Tokai University, Kanagawa-Ken, Japan.

Nephron
|January 1, 1989
PubMed

Three patients with IgA nephropathy associated with myasthenia gravis are described. In all 3 cases, myasthenia gravis emerged after the discovery of glomerulonephritis. Myasthenic symptoms were improved by thymectomy in 2 cases, but progression of the renal disease was not improved. Some systemic abnormalities, including immunological aberrations, were observed in these two disorders. It is postulated that T cell abnormalities in IgA nephropathy might be independent of the development of myasthenia gravis.

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