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Perinatal Tuberculosis: Is It a Forgotten Disease?

Laura Ferreras-Antolín1, Pilar Caro-Aguilera1, Estela Pérez-Ruíz1

  • 1From the Paediatric Infectious Diseases Unit, and Paediatric Respiratory Unit, Department of Paediatrics, Malaga Regional University Hospital, Málaga, Spain.

The Pediatric Infectious Disease Journal
|December 1, 2017
PubMed

Insights

Perinatal tuberculosis, a rare but serious condition, presents diagnostic challenges. Early consideration in at-risk mothers with respiratory issues unresponsive to antibiotics is crucial for timely intervention.

Area of Science:

  • Perinatology
  • Infectious Diseases
  • Pulmonology

Background:

  • Perinatal tuberculosis (TB) is a rare condition with significant maternal and infant mortality.
  • Diagnosis is often delayed due to non-specific symptoms and low clinical suspicion.

Observation:

  • This report details four cases of perinatal TB managed over two decades in a Spanish tertiary hospital.
  • Patients presented with progressive respiratory symptoms and poor response to standard antibiotic treatments.

Findings:

  • Perinatal TB should be suspected in pregnant individuals with persistent respiratory symptoms and a history of exposure.
  • Bronchoscopy emerged as a valuable diagnostic procedure in these challenging cases.

Implications:

  • Increased awareness and diagnostic vigilance for perinatal TB are essential.
  • Prompt diagnosis and appropriate management can improve outcomes for mother and child.

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