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Psychobiotics: A new approach for treating mental illness?
Snigdha Misra1, Debapriya Mohanty2
1a Department of Nutrition and Dietetics, School of Health Sciences , International Medical University , Kuala Lumpur , Malaysia.
Critical Reviews in Food Science and Nutrition
|December 1, 2017
Summary
The gut microbiome influences mood and cognition. Beneficial gut bacteria, or probiotics, may improve mental health by delivering neuroactive compounds, offering a new approach to psychiatric disorders.
Area of Science:
- Neuroscience
- Microbiology
- Psychiatry
Background:
- The gut microbiome significantly impacts mood and cognition.
- Emerging research highlights the gut-brain axis in neuroscience.
- Gut bacteria influence inflammation, cortisol levels, and stress reactivity.
Purpose of the Study:
- To explore the role of gut bacteria in mental health.
- To define psychobiotics as live organisms benefiting psychiatric patients.
- To investigate the potential of microbiota modulation for psychiatric disorders.
Main Methods:
- Review of studies on gut bacteria and mental health.
- Analysis of the mechanisms by which probiotics affect neuroactivity.
- Conceptualization of psychobiotics based on existing research.
Main Results:
- Increased beneficial gut bacteria can reduce depression, anxiety, and neuroticism.
- Probiotics may lower cortisol levels and improve memory.
- Gut bacteria act as delivery vehicles for neuroactive compounds.
Conclusions:
- Psychobiotics offer a novel therapeutic avenue for psychiatric conditions.
- Modulating the intestinal microbiota may effectively manage psychiatric disorders.
- Further research into psychobiotics is warranted for clinical applications.
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