Related Experiment Video
Updated: Feb 17, 2026
Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
Published on: February 17, 2023
A new methanogen "Methanobrevibacter massiliense" isolated in a case of severe periodontitis
Hong T T Huynh1,2, Marion Pignoly1, Michel Drancourt3
1UFR Odontologie, Aix-Marseille Université, 27, Boulevard Jean Moulin, Marseille Cedex 5, France.
Background:
A few methanogens have been previously recovered from periodontitis lesions, yet their repertoire may not be completed. We recovered a previously unreported methanogen species in this situation.
Case Presentation:
A 64-year-old Caucasian woman was diagnosed with chronic, severe generalized periodontitis. In the presence of negative controls, an 18-month culture of periodontal pockets in anaerobe Hungate tube yielded "Methanobrevibacter massiliense" and Pyramidobacter piscolens.
Conclusions:
This case report provides evidence of the symbiotic strategy deployed by the methanogens and the anaerobes, and reports the first culture of a new methanogen, "M. massiliense".
