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Intralesional corticosteroid therapy for infantile hemangiomas
G M Sloan1, J F Reinisch, L S Nichter
1Division of Plastic Surgery, Childrens Hospital of Los Angeles.
Plastic and Reconstructive Surgery
|March 1, 1989
Summary
Intralesional corticosteroid injections effectively treated infantile hemangiomas in infants. The treatment demonstrated significant lesion reduction and was found to be safe with no major complications.
Area of Science:
- Pediatric Dermatology
- Vascular Anomalies
Background:
- Infantile hemangiomas are common benign vascular tumors.
- Treatment options for problematic hemangiomas can be limited.
Purpose of the Study:
- To evaluate the safety and efficacy of intralesional corticosteroid injections for infantile hemangiomas.
Main Methods:
- 31 hemangiomas in 30 infants (1-10 months) received 1-5 intralesional injections of betamethasone acetate and triamcinolone acetonide.
- Injections were spaced 6 weeks apart.
- Lesions were primarily located in the head and neck region.
Main Results:
- Complete resolution occurred in 13% of lesions.
- 32% showed >50% volume reduction, and 32% showed <50% reduction.
- 23% showed minimal change; no lesions progressed.
Conclusions:
- Intralesional corticosteroid injections are a safe and effective treatment for selected infantile hemangiomas.
- The procedure was well-tolerated without significant complications.