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Published on: March 27, 2018
In vitro trials of a wearable artificial kidney (WAK)
Nikolai A Bazaev1, Nataliya I Dorofeeva1, Nikita M Zhilo1
1National Research University of Electronic Technology, Moscow - Russian Federation.
Background:
This paper presents results of in vitro trials of a wearable artificial kidney (WAK).
Materials And Methods:
To carry out the trials, a test bench was developed. It consisted of a patient imitator, a tubing set and measuring equipment.
Results:
Our WAK can eliminate urea, uric acid and creatinine from spent dialysate with mean mass rates of 0.85 ± 0.1 g/h, 0.10 ± 0.04 g/h and 0.05 ± 0.01 g/h, respectively. Concentrations of Na+, Cl- and Ca2+ ions were kept in the 10% range from initial values. We demonstrated that our WAK can operate for 38 hours without having to replace expendable materials.
Conclusions:
The WAK that we developed can eliminate metabolites from spent dialysis fluid with mass rates that are sufficient to maintain stable, physiologically normal metabolite concentrations in patients' blood.
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