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Updated: Feb 17, 2026
Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Review shows that implementing a nationwide protocol for congenital diaphragmatic hernia was a key factor in reducing
L Storme1, J Boubnova2, S Mur1
1Lille coordinating center, Jeanne de Flandre Hospital, Lille Regional University Hospital, Lille, France.
Abstract:
The French Rare Disease Reference Center for congenital diaphragmatic hernia (CDH) was created in 2008, to implement a national protocol for foetuses and children with this serious condition. Neonatal mortality from CDH is 30-40%, mainly due to pulmonary hypoplasia and persistent pulmonary hypertension, and half of those who live have high respiratory, nutritional and digestive morbidity. CDH management requires long-term and specialised multidisciplinary care. It has been well established that a standardised management protocol improves the prognosis of children with CDH.
Conclusion:
Organising health care and implementing a nationwide French protocol were key factors for reducing mortality and morbidity from CDH.
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