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Cardiovascular magnetic resonance elastography: A review.

Saad Khan1, Faisal Fakhouri1,2, Waqas Majeed1

  • 1Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

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|December 2, 2017
PubMed
Summary

Magnetic resonance elastography (MRE) non-invasively measures tissue stiffness. This technique quantifies myocardial and aortic stiffness, offering insights into cardiovascular diseases like hypertension and aneurysms.

Keywords:
aortic MREaortic stiffnesscardiac MREheart failuremagnetic resonance elastography (MRE)myocardial stiffnessshear stiffness

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Area of Science:

  • Cardiovascular research
  • Biomedical engineering
  • Medical imaging

Background:

  • Cardiovascular diseases are a leading global cause of death.
  • Altered myocardial and aortic stiffness is linked to various conditions, including hypertension, ischemia, and aneurysms.
  • Tissue stiffness can serve as a crucial biomarker for conditions like preserved ejection fraction diastolic dysfunction and aortic aneurysm rupture potential.

Purpose of the Study:

  • To review the technical aspects of magnetic resonance elastography (MRE).
  • To highlight the applications of MRE in quantifying myocardial and aortic stiffness.
  • To discuss the role of MRE in assessing various cardiovascular disease states.

Main Methods:

  • Magnetic Resonance Elastography (MRE) is a non-invasive phase-contrast magnetic resonance imaging technique.
  • MRE measures the mechanical properties of tissues, specifically stiffness.
  • This review synthesizes existing literature on MRE's technical details and clinical applications.

Main Results:

  • MRE enables non-invasive quantification of myocardial stiffness.
  • MRE allows for non-invasive assessment of aortic stiffness.
  • The technique provides valuable data for diagnosing and managing cardiovascular diseases.

Conclusions:

  • Magnetic Resonance Elastography (MRE) is a promising non-invasive tool for assessing cardiovascular mechanical properties.
  • Quantifying myocardial and aortic stiffness using MRE can aid in the diagnosis and management of various cardiovascular diseases.
  • Further research and clinical integration of MRE are warranted to leverage its full potential in cardiovascular medicine.