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Updated: Feb 17, 2026

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
Published on: December 1, 2020
Translational Biomedical Informatics and Pharmacometrics Approaches in the Drug Interactions Research
Pengyue Zhang1, Heng-Yi Wu1, Chien-Wei Chiang1
1Department of Biomedical Informatics, College of Medicine, the Ohio State University, Columbus, Ohio, USA.
Abstract:
Drug interaction is a leading cause of adverse drug events and a major obstacle for current clinical practice. Pharmacovigilance data mining, pharmacokinetic modeling, and text mining are computation and informatic tools on integrating drug interaction knowledge and generating drug interaction hypothesis. We provide a comprehensive overview of these translational biomedical informatics methodologies with related databases. We hope this review illustrates the complementary nature of these informatic approaches and facilitates the translational drug interaction research.
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