[Unicentric Castleman's disease in cervical back space neck]

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Castleman disease is a rare, benign lymphoid proliferation with unicentric and multicentric clinical types.
• Histological variants include hyaline-vascular, plasma cellular, and mixed patterns.
• Commonly affects the mediastinum, abdomen, and neck.

Observation:

• A 21-year-old female presented with a left neck mass.
• MRI revealed a solid, heterogeneous, vascularized lesion in the posterior neck space with thoracic outlet extension.
• The mass displaced adjacent carotid, cervical, and visceral structures.

Findings:

• MRI demonstrated characteristic features of the neck mass, including signal intensities on T1 and T2 weighted images with fat saturation.
• Post-contrast administration showed moderate enhancement.
• Histopathological diagnosis confirmed the hyaline-vascular type of Castleman disease.

Implications:

• Magnetic resonance imaging is crucial for characterizing neck masses and defining their extent.
• Accurate diagnosis of Castleman disease through imaging aids in appropriate therapeutic planning.
• Integrating MRI findings into the differential diagnosis of neck masses improves patient management.