Related Experiment Video

Updated: Feb 17, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin
08:07

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Published on: March 24, 2023

2.3K

TMEM106B and myelination: rare leukodystrophy families reveal unexpected connections

Xiaolai Zhou1, Rosa Rademakers1

  • 1Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.

Brain : a Journal of Neurology
|December 2, 2017
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.4K
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

10.5K

Related Experiment Videos

Last Updated: Feb 17, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin
08:07

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin

Published on: March 24, 2023

2.3K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.4K
Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

10.5K

Related Concept Videos

Nervous Tissue: Myelin01:25

Nervous Tissue: Myelin

6.1K
The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
6.1K

Articles linked to this work by shared authors, journal, and citation graph.

Targeted single-nucleus sequencing of 39,800 neurons reveals extensive low-frequency somatic variants.

bioRxiv : the preprint server for biology·2026

Evaluating MAPT p.A152T as a risk factor for the 3R tauopathy Pick's disease.

Brain communications·2026

Trajectories of brain structure and function in young adult carriers of genetic frontotemporal dementia variants.

medRxiv : the preprint server for health sciences·2026

Clinical Associations of Cerebrospinal Fluid TMEM106B in Familial and Sporadic Frontotemporal Dementia.

JAMA neurology·2026

TNFAIP3 in M2 Macrophage Attenuates Subretinal Fibrosis in Laser-Induced Murine Model.

Investigative ophthalmology & visual science·2026

Lactylation-Associated Immune Metabolic Reprogramming Identifies S100A2 and S100A14 as Candidate Diagnostic Biomarkers in Primary Open-Angle Glaucoma: An Integrated Bulk and Single-Cell Transcriptomic Analysis.

Genes·2026

Target engagement and efficacy in disease-modifying trials of synuclein-related disorders.

Brain : a journal of neurology·2026

The genetic landscape of myotonic dystrophy type 1: insights from nearly one million genomes.

Brain : a journal of neurology·2026

White matter hyperintensity burden in amyotrophic lateral sclerosis: motor and survival correlates.

Brain : a journal of neurology·2026

Nerve growth factor metabolic dysfunction in Down's syndrome brains.

Brain : a journal of neurology·2026

Mitochondrial DNA damage elicits PINK1 upregulation in pontine cholinergic neurons in Parkinson's disease.

Brain : a journal of neurology·2026

Blood-brain barrier opening with focused ultrasound reduces neuromelanin in a non-human primate model.

Brain : a journal of neurology·2026

Rare missense variants identified by whole-genome sequencing in men with oligoasthenoteratozoospermia: An experimental study.

International journal of reproductive biomedicine·2026

Whole-Exome Sequencing Reveals the Genetic Landscape and Genotype-Phenotype Spectrum of Dystonia in a Chinese Cohort.

CNS neuroscience & therapeutics·2026

Genome-wide analysis of 439 mass spectrometry-based proteomic profiles in a population of 15,035 Scottish individuals.

Nature communications·2026

Generation of a human induced pluripotent stem cell line (PNUYHi004-A) from a patient with hereditary spastic paraplegia type 46 (SPG46) carrying compound heterozygous GBA2 variants.

Stem cell research·2026

Polygenic Risk Scores for Islet Autoantibody Positive Early-Stage Type 1 Diabetes Pre-Screening.

Diabetes, obesity & metabolism·2026

Analysis of Genomic Testing of Congenital Heart Disease in a Cohort From a Consanguineous Population.

Clinical genetics·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us