Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ferromagnetism01:31

Ferromagnetism

3.2K
Materials like iron, nickel, and cobalt consist of magnetic domains, within which the magnetic dipoles are arranged parallel to each other. The magnetic dipoles are rigidly aligned in the same direction within a domain by quantum mechanical coupling among the atoms. This coupling is so strong that even thermal agitation at room temperature cannot break it. The result is that each domain has a net dipole moment. However, some materials have weaker coupling, and are ferromagnetic at lower...
3.2K
The Early Endosome: Endocytosis of Transferrin01:28

The Early Endosome: Endocytosis of Transferrin

4.9K
Essential proteins such as insulin or low-density lipoprotein (LDL) and micronutrients such as iron enter a eukaryotic cell through receptor-mediated endocytosis. Subsequently, the early endosomes fuse with the vesicles containing such receptor-ligand complexes and play a vital role in sorting the incoming ligands and receptors. While the ligands are either degraded inside the vesicle or released into the cytosol, their receptors are returned to the plasma membrane for further rounds of...
4.9K
Steel Manufacturing01:26

Steel Manufacturing

1.5K
Steel manufacturing is a multi-stage process that begins by smelting iron ore into cast iron in a blast furnace. This initial stage involves layering iron ore with coke, a type of fuel, and crushed limestone within the furnace. The coke is ignited with a high volume of air, leading to the creation of carbon monoxide, which acts to reduce the iron ore to pure iron.
During this smelting process, limestone plays a crucial role by forming slag. Slag captures impurities within the molten iron, such...
1.5K
Ferrocement01:30

Ferrocement

834
Ferro-cement is a distinctive construction material that represents an innovative variant of reinforced concrete, characterized by its unique composition and the method by which it is formed. Unlike standard reinforced concrete, which relies on larger steel bars for reinforcement, ferro-cement utilizes densely packed layers of mesh or fine rods, fully encased in cement mortar. This composition allows for the creation of structures that are significantly thinner and more flexible than their...
834
Eddy Currents01:25

Eddy Currents

2.7K
Since eddy currents occur only in conductors, magnets can separate metals from other materials. For example, in a recycling center, trash is dumped in batches down a ramp, beneath which lies a powerful magnet. Conductors in the trash are slowed by eddy currents, while nonmetals in the trash move on, separating from the metals. This works for all metals, not just ferromagnetic ones.
Other major applications of eddy currents appear in metal detectors and the braking systems of trains and roller...
2.7K
Necrosis01:16

Necrosis

6.7K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
6.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthetic Organisms Simplify Biology.

Cell·2019
Same author

High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy.

Science advances·2018
Same author

Toward a Choate View of Fate.

Cell·2018
Same author

Modulation of Threat Response in Larval Zebrafish.

Methods in molecular biology (Clifton, N.J.)·2018
Same author

Chemical Screening in Zebrafish.

Methods in molecular biology (Clifton, N.J.)·2016
Same author

Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.

Nature chemical biology·2016
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
See all related articles

Related Experiment Video

Updated: Feb 17, 2026

Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle
05:05

Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle

Published on: November 4, 2011

21.7K

The Ferrous Awakens.

Andrew J Rennekamp

    Cell
    |December 2, 2017
    PubMed
    Summary
    This summary is machine-generated.

    New research suggests inducing ferroptosis, a form of regulated cell death, may prevent cancer relapses. This discovery offers hope for improved cancer treatment outcomes and patient survival.

    More Related Videos

    Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
    04:01

    Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

    Published on: March 15, 2024

    2.0K
    Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
    10:23

    Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

    Published on: December 13, 2016

    10.5K

    Related Experiment Videos

    Last Updated: Feb 17, 2026

    Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle
    05:05

    Labeling Stem Cells with Ferumoxytol, an FDA-Approved Iron Oxide Nanoparticle

    Published on: November 4, 2011

    21.7K
    Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
    04:01

    Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

    Published on: March 15, 2024

    2.0K
    Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
    10:23

    Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

    Published on: December 13, 2016

    10.5K

    Area of Science:

    • Oncology
    • Cellular Biology
    • Biochemistry

    Background:

    • Cancer relapse remains a significant challenge in patient treatment.
    • Understanding regulated cell death pathways is crucial for novel therapeutic strategies.

    Purpose of the Study:

    • To explore the potential of inducing ferroptosis for preventing cancer relapse.
    • To investigate the mechanisms underlying ferroptosis in the context of cancer recurrence.

    Main Methods:

    • Utilizing in vitro cancer cell models.
    • Employing biochemical assays to measure ferroptosis.
    • Analyzing gene expression related to cell death pathways.

    Main Results:

    • Demonstrated that inducing ferroptosis can inhibit cancer cell survival.
    • Identified specific molecular triggers for ferroptosis in cancer cells.
    • Observed a reduction in cancer cell proliferation post-ferroptosis induction.

    Conclusions:

    • Inducing ferroptosis presents a promising strategy for preventing cancer relapse.
    • Targeting ferroptosis could lead to novel therapeutic interventions for various cancer types.