From ancestral peptides to designed proteins

Vikram Alva1, Andrei N Lupas1

  • 1Department of Protein Evolution, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

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Protein Structure Is Critical to Its Biological Function
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Mitochondrial Precursor Proteins

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Conservation of Protein Domains Over Different Proteins

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Translocation of Proteins into the Mitochondria

Mitochondrial precursors are translocated to the internal subcompartments via independent mechanisms involving distinct protein machineries called translocases.
Sorting of outer membrane proteins:
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Conserved Binding Sites

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