Related Experiment Video
Updated: Feb 17, 2026

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
Published on: February 23, 2019
Tracking word semantic change in biomedical literature
1College of Computing and Informatics, 3141 Chestnut Street, Drexel University, Philadelphia, PA 19104, USA.
Abstract:
Up to this point, research on written scholarly communication has focused primarily on syntactic, rather than semantic, analyses. Consequently, we have yet to understand semantic change as it applies to disciplinary discourse. The objective of this study is to illustrate word semantic change in biomedical literature. To that end, we identify a set of representative words in biomedical literature based on word frequency and word-topic probability distributions. A word2vec language model is then applied to the identified words in order to measure word- and topic-level semantic changes. We find that for the selected words in PubMed, overall, meanings are becoming more stable in the 2000s than they were in the 1980s and 1990s. At the topic level, the global distance of most topics (19 out of 20 tested) is declining, suggesting that the words used to discuss these topics are stabilizing semantically. Similarly, the local distance of most topics (19 out of 20) is also declining, showing that the meanings of words from these topics are becoming more consistent with those of their semantic neighbors. At the word level, this paper identifies two different trends in word semantics, as measured by the aforementioned distance metrics: on the one hand, words can form clusters with their semantic neighbors, and these words, as a cluster, coevolve semantically; on the other hand, words can drift apart from their semantic neighbors while nonetheless stabilizing in the global context. In relating our work to language laws on semantic change, we find no overwhelming evidence to support either the law of parallel change or the law of conformity.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
07:50A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Related Concept Videos
Improving Translational Accuracy
Improving Translational Accuracy
Anatomical Terminology
Leaky Scanning
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Proteins: From Genes to Degradation
Transcription is the synthesis of RNA...