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Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
Published on: November 27, 2019
Network meta-analysis: drawing conclusions regarding trials of psychosocial interventions for bipolar disorder
David J Miklowitz1, Andrea Cipriani2, Guy M Goodwin2
1David J. Miklowitz, PhD, Department of Psychiatry, University of California, Los Angeles (UCLA) School of Medicine, Los Angeles, California, USA and University Department of Psychiatry, University of Oxford, Oxford, UK; Andrea Cipriani, MD, PhD, Guy M. Goodwin, FMedSci, University Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK dmiklowitz@mednet.ucla.edu.
Abstract:
Network meta-analysis (NMA) is a statistical technique for making direct and indirect comparisons between different treatment and control groups. Despite its many advantages, NMA may be misleading when evaluating networks that are disconnected, inconsistent or of low reliability and validity. We review how well the analysis of trials of adjunctive psychosocial treatment in bipolar disorder is served by NMA. We conclude with recommendations for future treatment trials in bipolar disorder and guidelines for NMAs.
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