Related Experiment Video
Updated: Feb 17, 2026

Femoral Bone Marrow Aspiration in Live Mice
Published on: July 5, 2014
Bone marrow aspirations in oncological patients: experience from an in-house standard in paediatrics
Harald Sauer1, Stefan Graeber2, Ulla Lieser3
1Clinic for Pediatric Cardiology, University Hospital of Saarland, 66421, Homburg, Germany. harald.sauer@uks.eu.
Background:
Nearly all paediatric patients require deep sedation when undergoing bone marrow aspiration (BMA). We analyzed the data from our protocols documented in a standardised procedure for bone marrow puncture over a period of 2 years.
Methods:
Our standard included the documentation of personal data as well as vital parameters. In addition, we documented all medications administered, potential complications and required intervention measures, as necessary.
Results:
A total of 107 protocols were available for the evaluation. Our standard covered the usage of midazolam and S‑ketamine and resulted in complications in just 9 patients, which could be remedied using simple measures. For both active substances, the dosage necessary to reach sufficient deep analgosedation was significantly higher for patients under 24 months of age.
Conclusions:
Our standard for BMA provides a practical and feasible procedure. In addition to good examination conditions, our standard also helps ensure the safety of our patients.
More Related Videos
09:57Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
06:48In Ovo Xenografting of Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells (PDX-ALL)
Published on: August 1, 2025