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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

Sidharth V Puram1, Itay Tirosh2, Anuraag S Parikh1

  • 1Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA; Department of Otology and Laryngology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|December 5, 2017
PubMed

Keywords:
epithelial-to-mesenchymal transitionhead and neck squamous cell carcinomaintra-tumoral heterogeneitymetastasisscRNA-seqsingle-cell RNA sequencingtumor microenvironment

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