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Giardia duodenalis mouse model for the development of novel antigiardial agents

Rebecca J Abraham1, Mark O'Dea2, Bertha Rusdi2

  • 1Murdoch University, 90 South Street, Murdoch, Western Australia 6150, Australia; The University of Adelaide School of Animal and Veterinary Science, Mudla Wirra Rd, Roseworthy, South Australia 5352, Australia.

Journal of Microbiological Methods
|December 5, 2017
PubMed

Keywords:
Drug discoveryGiardiasisInfection model

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Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...